Human PHOS (PDC) activation kit by CRISPRa

CAT#: GA103430

PDC CRISPRa kit - CRISPR gene activation of human phosducin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDC
• Locus ID: 5132
• Kit Components:

  GA103430G1, PHOS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103430G2, PHOS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103430G3, PHOS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002597, NM_022576, NM_022577
• Synonyms: MEKA; PHD; PhLOP; PhLP
• Summary: 'This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'