Human ENPP3 activation kit by CRISPRa

CAT#: GA103466

ENPP3 CRISPRa kit - CRISPR gene activation of human ectonucleotide pyrophosphatase/phosphodiesterase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ENPP3
• Locus ID: 5169
• Kit Components:

  GA103466G1, ENPP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103466G2, ENPP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103466G3, ENPP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005021, NR_133007
• Synonyms: B10; CD203c; NPP3; PD-IBETA; PDNP3
• Summary: 'The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Oct 2015]'