Human PFDN5 activation kit by CRISPRa

CAT#: GA103495

PFDN5 CRISPRa kit - CRISPR gene activation of human prefoldin subunit 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PFDN5
• Locus ID: 5204
• Kit Components:

  GA103495G1, PFDN5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103495G2, PFDN5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103495G3, PFDN5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002624, NM_145896, NM_145897
• Synonyms: MM-1; MM1; PFD5
• Summary: 'This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'