Human PHEX activation kit by CRISPRa

CAT#: GA103525

PHEX CRISPRa kit - CRISPR gene activation of human phosphate regulating endopeptidase homolog X-linked

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PHEX
• Locus ID: 5251
• Kit Components:

  GA103525G1, PHEX gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103525G2, PHEX gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103525G3, PHEX gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000444, NM_001282754
• Synonyms: HPDR; HPDR1; HYP; HYP1; LXHR; PEX; XLH
• Summary: 'The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]'