Human PIGF activation kit by CRISPRa

CAT#: GA103548

PIGF CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class F

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGF
• Locus ID: 5281
• Kit Components:

  GA103548G1, PIGF gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103548G2, PIGF gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103548G3, PIGF gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002643, NM_173074
• Synonyms: MGC32646; MGC33136
• Summary: 'This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'