Human PIK3CB activation kit by CRISPRa

CAT#: GA103556

PIK3CB CRISPRa kit - CRISPR gene activation of human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIK3CB
• Locus ID: 5291
• Kit Components:

  GA103556G1, PIK3CB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103556G2, PIK3CB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103556G3, PIK3CB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256045, NM_006219
• Synonyms: P110BETA; PI3K; PI3KBETA; PIK3C1
• Summary: 'This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]'