Human PI 3 Kinase p85 beta (PIK3R2) activation kit by CRISPRa

CAT#: GA103561

PIK3R2 CRISPRa kit - CRISPR gene activation of human phosphoinositide-3-kinase regulatory subunit 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIK3R2
• Locus ID: 5296
• Kit Components:

  GA103561G1, PI 3 Kinase p85 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103561G2, PI 3 Kinase p85 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103561G3, PI 3 Kinase p85 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005027, NR_073517, NR_162071
• Synonyms: MPPH; MPPH1; p85; p85-BETA; P85B
• Summary: 'Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Apr 2019]'