Human Phospholipase C beta 2 (PLCB2) activation kit by CRISPRa

CAT#: GA103590

PLCB2 CRISPRa kit - CRISPR gene activation of human phospholipase C beta 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLCB2
• Locus ID: 5330
• Kit Components:

  GA103590G1, Phospholipase C beta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103590G2, Phospholipase C beta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103590G3, Phospholipase C beta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001284297, NM_001284298, NM_001284299, NM_004573
• Synonyms: PLC-beta-2
• Summary: 'The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017]'