Human PLP2 activation kit by CRISPRa

CAT#: GA103613

PLP2 CRISPRa kit - CRISPR gene activation of human proteolipid protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PLP2
• Locus ID: 5355
• Kit Components:

  GA103613G1, PLP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103613G2, PLP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103613G3, PLP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002668
• Synonyms: A4; A4LSB
• Summary: 'This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked cognitive disability. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010]'