Human POLD1 activation kit by CRISPRa

CAT#: GA103647

POLD1 CRISPRa kit - CRISPR gene activation of human DNA polymerase delta 1, catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: POLD1
• Locus ID: 5424
• Kit Components:

  GA103647G1, POLD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103647G2, POLD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103647G3, POLD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256849, NM_002691, NR_046402, NM_001308632
• Synonyms: CDC2; CRCS10; MDPL; POLD
• Summary: 'This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]'