Human PPEF1 activation kit by CRISPRa

CAT#: GA103693

PPEF1 CRISPRa kit - CRISPR gene activation of human protein phosphatase with EF-hand domain 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPEF1
• Locus ID: 5475
• Kit Components:

  GA103693G1, PPEF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103693G2, PPEF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103693G3, PPEF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006240, NM_152223, NM_152224, NM_152225, NM_152226
• Synonyms: PP7; PPEF; PPP7C; PPP7CA
• Summary: 'This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008]'