Human PP5 (PPP5C) activation kit by CRISPRa

CAT#: GA103735

PPP5C CRISPRa kit - CRISPR gene activation of human protein phosphatase 5 catalytic subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP5C
• Locus ID: 5536
• Kit Components:

  GA103735G1, PP5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103735G2, PP5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103735G3, PP5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204284, NM_006247
• Synonyms: PP5; PPP5; PPT
• Summary: 'This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]'