Human PRIM1 activation kit by CRISPRa

CAT#: GA103752

PRIM1 CRISPRa kit - CRISPR gene activation of human DNA primase subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRIM1
• Locus ID: 5557
• Kit Components:

  GA103752G1, PRIM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103752G2, PRIM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103752G3, PRIM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000946
• Synonyms: p49
• Summary: 'The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008]'