Human PKC delta (PRKCD) activation kit by CRISPRa

CAT#: GA103770

PRKCD CRISPRa kit - CRISPR gene activation of human protein kinase C delta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PRKCD
• Locus ID: 5580
• Kit Components:

  GA103770G1, PKC delta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103770G2, PKC delta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103770G3, PKC delta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001316327, NM_006254, NM_212539, NM_001354676, NM_001354678, NM_001354679, NM_001354680
• Synonyms: ALPS3; CVID9; MAY1; nPKC-delta; PKCD
• Summary: 'The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. [provided by RefSeq, Aug 2017]'