Human Enterokinase (TMPRSS15) activation kit by CRISPRa

CAT#: GA103830

TMPRSS15 CRISPRa kit - CRISPR gene activation of human transmembrane serine protease 15

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMPRSS15
• Locus ID: 5651
• Kit Components:

  GA103830G1, Enterokinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103830G2, Enterokinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103830G3, Enterokinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002772
• Synonyms: ENTK; PRSS7
• Summary: 'This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008]'