Human Phosphoserine phosphatase (PSPH) activation kit by CRISPRa

CAT#: GA103889

PSPH CRISPRa kit - CRISPR gene activation of human phosphoserine phosphatase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PSPH
• Locus ID: 5723
• Kit Components:

  GA103889G1, Phosphoserine phosphatase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103889G2, Phosphoserine phosphatase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103889G3, Phosphoserine phosphatase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004577, NM_001370503, NM_001370506, NM_001370507, NM_001370508, NM_001370510, NM_001370512, NM_001370515, NM_001370516, NM_001370518, NM_001370519, NM_001370520, NM_001370522, NM_001370504, NM_001370505, NM_001370509, NM_001370511, NM_001370513, NM_001370514, NM_001370517, NM_001370521
• Synonyms: PSP; PSPHD
• Summary: 'The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]'