Human Pentraxin 3 (PTX3) activation kit by CRISPRa

CAT#: GA103950

PTX3 CRISPRa kit - CRISPR gene activation of human pentraxin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PTX3
• Locus ID: 5806
• Kit Components:

  GA103950G1, Pentraxin 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103950G2, Pentraxin 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103950G3, Pentraxin 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002852
• Synonyms: TNFAIP5; TSG-14
• Summary: 'This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]'