Human GPBB (PYGB) activation kit by CRISPRa

CAT#: GA103969

PYGB CRISPRa kit - CRISPR gene activation of human glycogen phosphorylase B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PYGB
• Locus ID: 5834
• Kit Components:

  GA103969G1, GPBB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103969G2, GPBB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103969G3, GPBB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002862
• Synonyms: GPBB
• Summary: 'The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. [provided by RefSeq, Jul 2008]'