Human Rab4 (RAB4A) activation kit by CRISPRa

CAT#: GA103981

RAB4A CRISPRa kit - CRISPR gene activation of human RAB4A, member RAS oncogene family

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAB4A
• Locus ID: 5867
• Kit Components:

  GA103981G1, Rab4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103981G2, Rab4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103981G3, Rab4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271998, NM_004578, NR_073545
• Synonyms: HRES-1; HRES-1/RAB4; HRES1; RAB4
• Summary: 'This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]'