Human RBP4 activation kit by CRISPRa

CAT#: GA104054

RBP4 CRISPRa kit - CRISPR gene activation of human retinol binding protein 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RBP4
• Locus ID: 5950
• Kit Components:

  GA104054G1, RBP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104054G2, RBP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104054G3, RBP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001323517, NM_001323518, NM_006744
• Synonyms: MCOPCB10; RDCCAS
• Summary: ' This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]'