Human c Rel (REL) activation kit by CRISPRa
CAT#: GA104063
REL CRISPRa kit - CRISPR gene activation of human REL proto-oncogene, NF-kB subunit
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | REL |
Locus ID | 5966 |
Kit Components | GA104063G1, c Rel gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104063G2, c Rel gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104063G3, c Rel gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001291746, NM_002908 |
Synonyms | C-Rel |
Summary | 'This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN211878 | REL - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN211878BN | REL - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN211878LP | REL - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN211878RB | REL - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN411878 | REL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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