Human RENBP activation kit by CRISPRa

CAT#: GA104069

RENBP CRISPRa kit - CRISPR gene activation of human renin binding protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RENBP
• Locus ID: 5973
• Kit Components:

  GA104069G1, RENBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104069G2, RENBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104069G3, RENBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002910
• Synonyms: RBP; RNBP
• Summary: 'The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]'