Human RFX2 activation kit by CRISPRa

CAT#: GA104084

RFX2 CRISPRa kit - CRISPR gene activation of human regulatory factor X2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RFX2
• Locus ID: 5990
• Kit Components:

  GA104084G1, RFX2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104084G2, RFX2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104084G3, RFX2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000635, NM_134433, N23669
• Synonyms: FLJ14226
• Summary: 'This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]'