Human RNF6 activation kit by CRISPRa

CAT#: GA104122

RNF6 CRISPRa kit - CRISPR gene activation of human ring finger protein 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RNF6
• Locus ID: 6049
• Kit Components:

  GA104122G1, RNF6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104122G2, RNF6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104122G3, RNF6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005977, NM_183043, NM_183044, NM_183045
• Synonyms: DKFZp686P0776
• Summary: 'The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]'