Human ROS1 activation kit by CRISPRa

CAT#: GA104133

ROS1 CRISPRa kit - CRISPR gene activation of human ROS proto-oncogene 1, receptor tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ROS1
• Locus ID: 6098
• Kit Components:

  GA104133G1, ROS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104133G2, ROS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104133G3, ROS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_002944
• Synonyms: c-ros-1; MCF3; ROS
• Summary: 'This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq, Jul 2008]'