Human RPL10 activation kit by CRISPRa

CAT#: GA104152

RPL10 CRISPRa kit - CRISPR gene activation of human ribosomal protein L10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPL10
• Locus ID: 6134
• Kit Components:

  GA104152G1, RPL10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104152G2, RPL10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104152G3, RPL10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256577, NM_001256580, NM_001303624, NM_001303625, NM_001303626, NM_006013, NM_032241, NR_026898
• Synonyms: AUTSX5; DXS648; DXS648E; L10; NOV; QM
• Summary: 'This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]'