Human RSK3 (RPS6KA2) activation kit by CRISPRa

CAT#: GA104198

RPS6KA2 CRISPRa kit - CRISPR gene activation of human ribosomal protein S6 kinase A2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RPS6KA2
• Locus ID: 6196
• Kit Components:

  GA104198G1, RSK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104198G2, RSK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104198G3, RSK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001006932, NM_001318936, NM_001318937, NM_001318938, NM_021135
• Synonyms: HU-2; MAPKAPK1C; p90-RSK3; p90RSK2; pp90RSK3; RSK; RSK3; S6K-alpha; S6K-alpha2
• Summary: 'This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2016]'