Human RREB1 activation kit by CRISPRa

CAT#: GA104229

RREB1 CRISPRa kit - CRISPR gene activation of human ras responsive element binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RREB1
• Locus ID: 6239
• Kit Components:

  GA104229G1, RREB1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104229G2, RREB1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104229G3, RREB1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001003698, NM_001003699, NM_001003700, NM_001168344, NM_002955
• Synonyms: FINB; HNT; LZ321; RREB-1; Zep-1
• Summary: The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]