Human Retinoid X Receptor alpha (RXRA) activation kit by CRISPRa

CAT#: GA104239

RXRA CRISPRa kit - CRISPR gene activation of human retinoid X receptor alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RXRA
• Locus ID: 6256
• Kit Components:

  GA104239G1, Retinoid X Receptor alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104239G2, Retinoid X Receptor alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104239G3, Retinoid X Receptor alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001291920, NM_001291921, NM_002957
• Synonyms: NR2B1
• Summary: 'Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]'