Human MCP3 (CCL7) activation kit by CRISPRa

CAT#: GA104317

CCL7 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCL7
• Locus ID: 6354
• Kit Components:

  GA104317G1, MCP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104317G2, MCP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104317G3, MCP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006273
• Synonyms: FIC; MARC; MCP-3; MCP3; NC28; SCYA6; SCYA7
• Summary: 'This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]'