Human Eotaxin (CCL11) activation kit by CRISPRa
CAT#: GA104319
CCL11 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 11
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | CCL11 |
Locus ID | 6356 |
Kit Components | GA104319G1, Eotaxin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104319G2, Eotaxin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104319G3, Eotaxin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_002986 |
Synonyms | SCYA11 |
Summary | 'This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]' |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN404726 | CCL11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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