Human Semaphorin 3F (SEMA3F) activation kit by CRISPRa

CAT#: GA104358

SEMA3F CRISPRa kit - CRISPR gene activation of human semaphorin 3F

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SEMA3F
• Locus ID: 6405
• Kit Components:

  GA104358G1, Semaphorin 3F gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104358G2, Semaphorin 3F gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104358G3, Semaphorin 3F gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001318798, NM_001318800, NM_004186
• Synonyms: SEMA-IV; SEMA4; SEMAK
• Summary: 'This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]'