Human ST8SIA1 activation kit by CRISPRa

CAT#: GA104415

ST8SIA1 CRISPRa kit - CRISPR gene activation of human ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ST8SIA1
• Locus ID: 6489
• Kit Components:

  GA104415G1, ST8SIA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104415G2, ST8SIA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104415G3, ST8SIA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304450, NM_003034
• Synonyms: GD3S; SIAT8; SIAT8-A; SIAT8A; ST8SiaI
• Summary: 'Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2015]'