Human SLC2A2 activation kit by CRISPRa

CAT#: GA104439

SLC2A2 CRISPRa kit - CRISPR gene activation of human solute carrier family 2 member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC2A2
• Locus ID: 6514
• Kit Components:

  GA104439G1, SLC2A2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104439G2, SLC2A2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104439G3, SLC2A2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000340, NM_001278658, NM_001278659
• Synonyms: GLUT2
• Summary: 'This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]'