Human BRG1 (SMARCA4) activation kit by CRISPRa
CAT#: GA104511
SMARCA4 CRISPRa kit - CRISPR gene activation of human SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | SMARCA4 |
Locus ID | 6597 |
Kit Components | GA104511G1, BRG1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104511G2, BRG1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104511G3, BRG1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001128844, NM_001128845, NM_001128846, NM_001128847, NM_001128848, NM_001128849, NM_003072 |
Synonyms | BAF190; BAF190A; BRG1; CSS4; hSNF2b; MRD16; RTPS2; SNF2; SNF2L4; SNF2LB; SWI2 |
Summary | 'The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]' |
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Other Versions
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KN219258 | SMARCA4 - human gene knockout kit via CRISPR, HDR mediated |
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KN219258BN | SMARCA4 - human gene knockout kit via CRISPR, HDR mediated |
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KN219258LP | SMARCA4 - human gene knockout kit via CRISPR, HDR mediated |
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KN219258RB | SMARCA4 - human gene knockout kit via CRISPR, HDR mediated |
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KN419258 | SMARCA4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
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