Human Smoothened (SMO) activation kit by CRISPRa

CAT#: GA104521

SMO CRISPRa kit - CRISPR gene activation of human smoothened, frizzled class receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SMO
• Locus ID: 6608
• Kit Components:

  GA104521G1, Smoothened gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104521G2, Smoothened gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104521G3, Smoothened gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005631
• Synonyms: FZD11; Gx; SMOH
• Summary: 'The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010]'