Human beta Synuclein (SNCB) activation kit by CRISPRa

CAT#: GA104533

SNCB CRISPRa kit - CRISPR gene activation of human synuclein beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNCB
• Locus ID: 6620
• Kit Components:

  GA104533G1, beta Synuclein gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104533G2, beta Synuclein gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104533G3, beta Synuclein gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001502, NM_001318034, NM_001318035, NM_001318036, NM_001318037, NM_003085, NM_001363140
• Synonyms: beta-synuclein; synuclein, beta
• Summary: 'This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]'