Human SNRPE activation kit by CRISPRa

CAT#: GA104547

SNRPE CRISPRa kit - CRISPR gene activation of human small nuclear ribonucleoprotein polypeptide E

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNRPE
• Locus ID: 6635
• Kit Components:

  GA104547G1, SNRPE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104547G2, SNRPE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104547G3, SNRPE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304464, NM_003094, NR_130746, NM_001328637, NM_001328638
• Synonyms: B-raf; HYPT11; Sm-E; SME
• Summary: 'The protein encoded by this gene is a core component of U small nuclear ribonucleoproteins, which are key components of the pre-mRNA processing spliceosome. The encoded protein plays a role in the 3' end processing of histone transcripts. This protein is one of the targets in the autoimmune disease systemic lupus erythematosus, and mutations in this gene have been associated with hypotrichosis. Several pseudogenes of this gene have been identified. [provided by RefSeq, Jun 2016]'