Human SOAT 1 (SOAT1) activation kit by CRISPRa

CAT#: GA104556

SOAT1 CRISPRa kit - CRISPR gene activation of human sterol O-acyltransferase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SOAT1
• Locus ID: 6646
• Kit Components:

  GA104556G1, SOAT 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104556G2, SOAT 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104556G3, SOAT 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252511, NM_001252512, NM_003101, NR_045530
• Synonyms: ACACT; ACAT; ACAT-1; ACAT1; SOAT; STAT
• Summary: 'The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]'