Human SREBP2 (SREBF2) activation kit by CRISPRa

CAT#: GA104619

SREBF2 CRISPRa kit - CRISPR gene activation of human sterol regulatory element binding transcription factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SREBF2
• Locus ID: 6721
• Kit Components:

  GA104619G1, SREBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104619G2, SREBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104619G3, SREBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004599, NR_103834
• Synonyms: bHLHd2; SREBP-2; SREBP2
• Summary: 'This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]'