Human SRP68 activation kit by CRISPRa

CAT#: GA104627

SRP68 CRISPRa kit - CRISPR gene activation of human signal recognition particle 68

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRP68
• Locus ID: 6730
• Kit Components:

  GA104627G1, SRP68 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104627G2, SRP68 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104627G3, SRP68 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001260502, NM_001260503, NM_014230, NR_048541
• Summary: 'This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]'