Human STXBP2 activation kit by CRISPRa

CAT#: GA104688

STXBP2 CRISPRa kit - CRISPR gene activation of human syntaxin binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: STXBP2
• Locus ID: 6813
• Kit Components:

  GA104688G1, STXBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104688G2, STXBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104688G3, STXBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001127396, NM_001272034, NM_006949, NR_073560
• Synonyms: FHL5; Hunc18b; MUNC18-2; pp10122; UNC18-2; UNC18B
• Summary: 'This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013]'