Human Neurokinin 1 Receptor (TACR1) activation kit by CRISPRa

CAT#: GA104728

TACR1 CRISPRa kit - CRISPR gene activation of human tachykinin receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TACR1
• Locus ID: 6869
• Kit Components:

  GA104728G1, Neurokinin 1 Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104728G2, Neurokinin 1 Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104728G3, Neurokinin 1 Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001058, NM_015727
• Synonyms: NK1R; NKIR; SPR; TAC1R
• Summary: 'This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]'