Human TCN2 activation kit by CRISPRa

CAT#: GA104796

TCN2 CRISPRa kit - CRISPR gene activation of human transcobalamin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TCN2
• Locus ID: 6948
• Kit Components:

  GA104796G1, TCN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104796G2, TCN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104796G3, TCN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000355, NM_001184726, NM_001190420
• Synonyms: D22S676; D22S750; II; TC; TC-2; TC2; TC II; TCII
• Summary: 'This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]'