Human Cripto1 (TDGF1) activation kit by CRISPRa

CAT#: GA104811

TDGF1 CRISPRa kit - CRISPR gene activation of human teratocarcinoma-derived growth factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TDGF1
• Locus ID: 6997
• Kit Components:

  GA104811G1, Cripto1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104811G2, Cripto1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104811G3, Cripto1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001174136, NM_003212
• Synonyms: CR; CRGF; CRIPTO
• Summary: 'This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]'