Human GRP94 (HSP90B1) activation kit by CRISPRa

CAT#: GA104966

HSP90B1 CRISPRa kit - CRISPR gene activation of human heat shock protein 90 beta family member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HSP90B1
• Locus ID: 7184
• Kit Components:

  GA104966G1, GRP94 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104966G2, GRP94 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104966G3, GRP94 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003299
• Synonyms: ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
• Summary: 'This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]'