Human CD252 (TNFSF4) activation kit by CRISPRa

CAT#: GA105022

TNFSF4 CRISPRa kit - CRISPR gene activation of human TNF superfamily member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TNFSF4
• Locus ID: 7292
• Kit Components:

  GA105022G1, CD252 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105022G2, CD252 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105022G3, CD252 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001297562, NM_003326
• Synonyms: CD134L; CD252; GP34; OX-40L; OX4OL; TXGP1
• Summary: 'This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]'