Human UGT8 activation kit by CRISPRa

CAT#: GA105076

UGT8 CRISPRa kit - CRISPR gene activation of human UDP glycosyltransferase 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UGT8
• Locus ID: 7368
• Kit Components:

  GA105076G1, UGT8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105076G2, UGT8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105076G3, UGT8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001128174, NM_001322112, NM_001322113, NM_001322114, NM_003360
• Synonyms: CGT; UGT4
• Summary: The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]