Human EIF4H activation kit by CRISPRa

CAT#: GA105139

EIF4H CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 4H

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EIF4H
• Locus ID: 7458
• Kit Components:

  GA105139G1, EIF4H gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105139G2, EIF4H gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105139G3, EIF4H gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022170, NM_031992
• Synonyms: eIF-4H; WBSCR1; WSCR1
• Summary: 'This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]'