Human TRIM26 activation kit by CRISPRa

CAT#: GA105273

TRIM26 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 26

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIM26
• Locus ID: 7726
• Kit Components:

  GA105273G1, TRIM26 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105273G2, TRIM26 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105273G3, TRIM26 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242783, NM_003449
• Synonyms: AFP; RNF95; ZNF173
• Summary: 'The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]'